Cross Kidney Transplantation

Thanks to many years of experience in cross-kidney transplantation, our team provided the chance of undergoing transplantation to several couples without the hope of transplantation. Two hopeless couples with no chance of receiving kidney from their relatives can get the chance of undergoing compatible healthy kidney transplantation by sharing their kidneys mutually. For this reason, the better description of cross-transplantation can be "kidney brotherhood". In the cases that living donor is present however kidney transplantation cannot be performed from relative due to blood group incompatibility or the presence of high antibody, life gift can be shared via cross transplantation method.

Two couples, who are registered in our cross transplantation program, are matched when blood group, age, gender values suit. The couples are introduced to each other when tissue and cross examinations of the eligible couples are result appropriate. The kidneys of both parties to be changed have to be balanced at key points such as age, tissue compatibility. Cross kidney transplantation can be performed with the acceptance of the patient and donor of two couples. In cross transplantation, two couples exchange kidneys with a previously planned simultaneously performed operation and they wake up from a healthy kidney transplantation operation.

The most common couples benefiting from cross kidney transplantation are recipients and donors with A - B or B – A group. These couples can find a suitable couple within weeks or months. For example, kidney exchange is performed between a couple of recipient with blood group A and a donor with blood group B, and a couple of recipient with blood group B and a donor with blood group A.

Kidney brotherhood is not only to solve ABO blood group incompatibility, but also provides an important opportunity to ensure undergoing transplantation of the couples with improper cross examination at the same time. There are couples, in which transplantation is not possible from relatives, as everything including blood group is appropriate in donor and recipient for transplantation however in cross examination severe rejection will be developed when kidney is received from relative. For example, lets think a couple, recipient with A and donor with 0 that cannot receive kidney from their relative due to high antibodies in the recipient despite blood group compliance. This couple may attain chance of transplantation with a couple in blood group 0 and donor’s blood group is A in the cross-list. Thus, also the recipients with blood group O, which is the most difficult match in the cross-transplantation list, are matched with this way. So, for patients with blood group O can be found from antigen-loaded patients that cannot receive kidney from donor with blood group O due to appropriate double-cross examination. Thus, the donor with blood group O gives kidney to the other recipient with blood group O, while the kidney is provided from donor from tissue group that antibodies in the blood will not attack to this patient loaded with high antigenic.

All possible facilities should be provided to the patients, who are bound to life with passion and waiting for kidney transplantation, in order to solve organ failure. Kidney brotherhood program was created to serve this purpose. It may be possible to convert two couples with no chance of kidney transplantation to two couples underwent transplantation by the most beautiful sharing with kidney brotherhood program. Performing cross-transplantation is also possible in order to increase histocompatibility between donor and recipient more. The greatest thrill for us is to attain one more person underwent kidney transplantation. Therefore, you can contact us to get information about our kidney brotherhood program.

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